Pipeline

Zerbaxa (ceftolozane/tazobactam)
Zerbaxa is a combination drug containing ceftolozane, a cephalosporin antibacterial drug, and tazobactam, a beta-lactamase inhibitor. Zerbaxa was approved by the FDA and the EMA to treat complicated intra-abdominal infections (cIAI) and complicated urinary tract infections (cUTI). Zerbaxa is put on sale by Merck & Co., Inc.
Collaboration: Astellas Pharma Inc.
Licensee: Cubist Pharmaceuticals
Official Website
https://www.merckconnect.com/zerbaxa/overview.html@
Baxdela (delafloxacin)
Baxdela is a fluoroquinolone antibiotic that exhibits activity against both
gram-positive and gram-negative pathogens, including MRSA. On 19th June
2017, the U.S. Food and Drug Administration (FDA) has approved Baxdela,
indicated in adults for the treatment of acute bacterial skin and skin
structure infections (ABSSSI).
Licensee: Melinta Therapeutics
Website
http://melinta.com/pipeline/baxdela/
Gram negative program
We have been investigating antibiotics targeting gram-negative and drug-resistant bacteria. Recently, we discovered WFQs with high activity and efflux-avoidance nature, and presented their profiles in ASM Microbe 2016 (News Release in 2016). We are looking for business partners to develop them (Contact Us)
Tumor microenvironment program
We have been investigating anti-tumor agents focused on tumor microenvironment.